Welcome to Division of Infectious Diseases

Department of Medicine, Faculty of Medicine

Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society

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Journal Session: Aug 9, 2011-Rilpivirine Issue

Rilpivirine versus efavirenz with tenofovir and emtricitabine in treatment-naive adults infected with HIV-1 (ECHO): a phase 3 randomised double-blind active-controlled trial Rotating Resident: Natapol K. Fellow: Paisan T. Rm 117 Internal Medicine Bldg. 09:00-10:00 On this July 16th issue of the Lancet, the results of 2 major phase III RCTs of Rilpivirine (TMC278), the newest NNRTI, in comparison with Efavirenz for ART-naive patients were introduced. 1. the ECHO study group: Jean-Michel Molina, et al. Rilpivirine versus efavirenz with tenofovir and emtricitabine in treatment-naive adults infected with HIV-1 (ECHO): a phase 3 randomised double-blind active-controlled trial. Lancet 2011; 378: 238–46. 2. the THRIVE study group: Calvin J Cohen, et al. Rilpivirine versus efavirenz with two background nucleoside or nucleotide reverse transcriptase inhibitors in treatment-naive adults infected with HIV-1 (THRIVE): a phase 3, randomised, non-inferiority trial. Lancet 2011; 378: 229–37. plus the comment by Schrijvers R, et al.Rilpivirine: a step forward in tailored HIV treatment. Lancet 2011; 378: 201-3. Everyone is welcome

Interesting Case Conference : Aug 3, 2011

case 1: 38 years old female, history of HIV infection for 13 years,presented with progressive dyspnea and bilateral leg edema for 3 months. Rotating resident : Natapol K. 1st year Fellow : Ratima I. Invited guest : Dr.Nattapong Jiemjariyatham. case 2 :63 years old monk, history of DM2,HT,Dyslipidemia, presented with RT nasal mass for 1 month , swelling and tenderness on RT leg for 1 week Rotating resident : Pitchaya K. 2 nd year Fellow : Suwimon K. Invited guest : Associate professor Dr. Ariya Jindamaporn,Ph.D. Rm 117 Internal Medicine Bldg. 09:00-10:00

Topic Review:Aug 2, 2011

Management of occupational exposures to HIV and recommendations for postexposure prophylaxis Rawiwan S. second-year resident Nontalee T. second-year fellow Rm 117 Internal Medicine Bldg 09:00-10:00 Suggested Readings 1. Updated U.S. Public Health Service Guidelines for the Management of Occupational Exposures to HIV and Recommendations for Postexposure Prophylaxis. MMWR 2005; 54: RR-9. 2. Raphael J. Landovitz, and Judith S. Currier. Postexposure Prophylaxis for HIV Infection. N Engl J Med 2009; 361:1768-75. 3. Ronald H. Goldschmidt. Occupational Postexposure Prophylaxis for HIV.Top HIV Med 2010; 18: 174-177.

Journal Session: July 27, 2011

Prevention of HIV-1 Infection with Early Antiretroviral Therapy the HPTN 052 Myron S Cohen, et al. N Engl J Med 2011 [Epub ahead of print] Editorial Comment: Antiretroviral Treatment as Prevention Scott M Hammer. N Engl J Med 2011 [Epub ahead of print] Fellow: Pornvimol Leethong Resident: Phichaya Kanjanabenja Rm 117 Internal Medicine Bldg 09:00-10:00

Topic Review: Aug 16, 2011-nosocomail CDAD

Topic Review: How to deal with nosocomial Clostidium difficile Pitak D. – 1st-yr fellow Nattapol – rotating resident Rm 117 Internal Medicine Bldg 09:00-10:00 Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA). Infection Control and Hospital Epidemiology 2010; 31:431-455 Preventing Transmission of Clostridium difficile: Is the Answer Blowing in the Wind? Clin Infect Dis 2010; 50: 1458-61.

Topic Review: Aug 16, 2011 nosocomial CDAD

Topic Review: How to deal with nosocomial Clostidium difficile Pitak D. – 1st-yr fellow Nattapol – rotating resident Rm 117 Internal Medicine Bldg 09:00-10:00 Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA). Infection Control and Hospital Epidemiology 2010; 31:431-455 Preventing Transmission of Clostridium difficile: Is the Answer Blowing in the Wind? Clin Infect Dis 2010; 50: 1458-61.



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